I've always had good success launching at Lighthouse Cove (free launch) and trolling between the Thames and Stoney point in 10-14 fow. You need shallow running lures that don't run below 8 ft. or you will hit bottom. Depending upon conditions I keep GPS speed between 2.8 & 4 mph. I put a large rubber core sinker about 3 ft. in front of the lure to help keep weeds off the lures and even then I still check the lures often. LSC is very weedy and especially after a blow can have lots of surface weeds to catch on your line. General rule of thumb to remember is stained water where you can't see your lure very deep go with bright colors like fluorescents, firetiger, lemonhead, white etc. Clear water: go with natural colors like Perch, walleye, 9 dollar bass, sucker, cisco, shad etc. Water color and light condition (sunny day vs cloudy day) will affect lure colour more than season will. Expect a whopper or two smallmouth, St. Clair has some brutes that are not the least bit shy about hitting even the biggest musky lures.
Just to note LSC musky opens 1st Sat. in June to Dec. 15 and good luck in Muskieville.